2024.05.06
Brief Bioinform" | Wu Song/Bai Chen team jointly develops molecular generation model InterDiff.
Recently, MoMed Biotech, in collaboration with Professor Wu Song's team from Shenzhen University, has developed a molecular generation model called InterDiff based on hotspots residues and interaction cues. This research was published in the top journal in the field of bioinformatics, Briefings in Bioinformatics. InterDiff utilizes a diffusion model as its core architecture and employs the technique of cue learning to guide the generation process of molecules, specifically targeting interactions with protein pocket residues.